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Publications

Peer-reviewed research

Journal Articles

2026
22
Liver organoids for chemical risk assessment: biological fidelity, standardization, and context-of-use frameworks
Yongbo Shin*, Hye-Ran Moon*, You Mie Lee, Myung Jin Son
Archives of Pharmacal Research 49: 941–954
21
Flexible and wireless ‘stick-and-detect’ sensor node based on laser-induced graphene for real-time temperature monitoring toward cold chain applications
Hak Jun Lee, Se Eung Ahn, Minhyuk Jung, Hye-ran Moon, Byunghoon Ryu
Chemical Engineering Journal
20
Statin-dye conjugates for selective targeting of KRAS mutant cancer cells
Hye-ran Moon*, Zhenying Cai*, Bo Kyung Cho*, Hyeyoun Chang, Seung Taek Hong, Jean J. Zhao, Ick Chan Kwon, Thomas M. Roberts, Bumsoo Han, Ju Hee Ryu
PLoS ONE 21(1): e0340189
2025
19
Targeting and exploiting macropinocytosis in cancer therapy
Hye-ran Moon*, Bo Kyung Cho*, Seung Hyun Kang, Ju Hee Ryu, Ick Chan Kwon
Journal of Controlled Release 113962
18
DNA Origami-Cyanine Nanocomplex for Precision Imaging of KRAS-Mutant Pancreatic Cancer Cells
Hye-ran Moon*, Yancheng Du*, Sae Rome Choi*, Seongmin Seo, Cih Cheng, Bennett D. Elzey, Jong Hyun Choi, Bumsoo Han
Advanced Science 12(19): 2410278
Hot Topic: MicrofluidicsFrontispiece
2024
17
Guidelines for manufacturing and application of organoids: Liver
Hye-ran Moon*, Seon Ju Mun*, Tae Hun Kim*, Hyemin Kim, Dukjin Kang, Suran Kim, Ji Hyun Shin, Dongho Choi, Sun-Ju Ahn, Myung Jin Son
International Journal of Stem Cells 17(2): 120
16
Review of Laser-Induced Graphene (LIG) Produced on Eco-Friendly Substrates
Hye-ran Moon, Byunghoon Ryu
International Journal of Precision Engineering and Manufacturing-Green Technology 1–16
15
New Ref-1/Ape1 Targeted Inhibitors Demonstrating Improved Potency for Clinical Applications in Multiple Cancer Types
Silpa Gampala, Hye-ran Moon, Randall Wireman, Jacqueline Peil, Sonia Kiran, Dana K. Mitchell, Kylee Brewster, et al.
Pharmacological Research 107092
2023
14
Microphysiological Systems as Reliable Drug Discovery and Evaluation Tools: Evolution from Innovation to Maturity
Hye-ran Moon, Nishanth Surianarayanan, Tarun Singh, Bumsoo Han
Biomicrofluidics 17(6)
13
Inkjet-printed morphogenesis of tumor-stroma interface using bi-cellular bioinks of collagen-poly(N-isopropyl acrylamide-co-methyl methacrylate) mixture
Cih Cheng, Naomi Deneke, Hye-ran Moon, Sae Rome Choi, Natalia Ospina-Munoz, Bennett Elzey, Chelsea Davis, George T.-C. Chiu, Bumsoo Han
Materials Today Advances 19: 100408
12
Optically induced electrothermal microfluidic tweezers in bio-relevant media
Kshitiz Gupta, Hye-ran Moon, Zhengwei Chen, Bumsoo Han, Nicolas G. Green, Steven T. Wereley
Scientific Reports 13(1): 9819
2022
11
Cells function as a ternary logic gate to decide migration direction under integrated chemical and fluidic cues
Hye-ran Moon, Soutick Saha, Andrew Mugler, Bumsoo Han
Lab on a Chip 23(4): 631–644
Lab on a Chip HOT Article 2023
10
Deduction of signaling mechanism from cellular responses to multiple cues
Soutick Saha, Hye-ran Moon, Bumsoo Han, Andrew Mugler
npj Systems Biology and Applications 8(1): 1–10
2021
09
Signal processing capacity of the cellular sensory machinery regulates the accuracy of chemotaxis under complex cues
Hye-ran Moon*, Soutick Saha*, Andrew Mugler, Bumsoo Han
iScience 24(11): 103242
08
Engineering of a functional pancreatic acinus with reprogrammed cancer cells by induced PTF1a expression
Stephanie M. Venis, Hye-ran Moon, Yi Yang, Sagar M. Utturkar, Stephen F. Konieczny, Bumsoo Han
Lab on a Chip 21(19): 3675–3685
Journal cover
07
Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: Exploiting this novel finding as a potential target
Silpa Gampala, Fenil Shah, Xiaoyu Lu, Hye-ran Moon, Olivia Babb, Nikkitha Umesh Ganesh, George Sandusky, et al.
Journal of Experimental & Clinical Cancer Research 40(1): 1–24
2020
06
An engineered pancreatic cancer model with intra-tumoral heterogeneity of driver mutations
Hye-ran Moon*, Altug Ozcelikkale*, Yi Yang, Bennett D. Elzey, Stephen F. Konieczny, Bumsoo Han
Lab on a Chip 20(20): 3720–3732
Journal back cover
05
Subtype-specific characterization of breast cancer invasion using a microfluidic tumor platform
Hye-ran Moon, Natalia Ospina-Muñoz, Victoria Noe-Kim, Yi Yang, Bennett D. Elzey, Stephen F. Konieczny, Bumsoo Han
PLoS ONE 15(6): e0234012
2019
04
Physical constraints on accuracy and persistence during breast cancer cell chemotaxis
Julien Varennes*, Hye-ran Moon*, Soutick Saha, Andrew Mugler, Bumsoo Han
PLoS Computational Biology 15(4): e1006961
2017
03
In vitro microfluidic models of tumor microenvironment to screen transport of drugs and nanoparticles
Altug Ozcelikkale, Hye-ran Moon, Michael Linnes, Bumsoo Han
WIREs Nanomedicine and Nanobiotechnology 9(5): e1460
Top 20 most downloaded
2015
02
Design of integrated light guide plate with functional structure of enhanced diffusion length for ultra-slim LED backlight unit
Hye-ran Moon, Min-Ho Shin, Jae-Yong Lee, Kyu-Jin Jang, Young-Ok Chung, Young-Joo Kim
Journal of Display Technology 11(1): 44–52
2014
01
Proposal and design of hybrid light guide plate based on aspheric concave surface and micropatterns to improve illuminance and color uniformity for LED display
Min-Ho Shin, Jae-Yong Lee, Hye-ran Moon, Young-Joo Kim
Japanese Journal of Applied Physics 53(8S2): 08MF01

Book Chapters

2024
02
Tumor-Microenvironment-on-Chip Platform for Assessing Drug Response in 3D Dynamic Culture
Hakan Berk Aydin, Hye-ran Moon, Bumsoo Han, Altug Ozcelikkale, Ahmet Acar
In: Z. Sumbalova Koledova (ed.), 3D Cell Culture Methods in Molecular Biology, vol. 2764 · Humana, New York · 265–278
2020
01
Engineered tumor models for cancer biology and treatment
Hye-ran Moon, Bumsoo Han
In: K. Park (ed.), Biomaterials for Cancer Therapeutics, 2nd ed. Woodhead Publishing · 423–443

Preprints

2026
01
Extravascular coagulation stabilizes pro-fibrotic stromal states via tumor-intrinsic PAR1 signaling in pancreatic ductal adenocarcinoma
Sae Rome Choi, Natalia Ospina-Muñoz, Hye-ran Moon, Bumsoo Han
Preprint Under review

* Equal contribution. Titles link to the publisher's page where a DOI is available. A complete and continuously updated list is available on Google Scholar.

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